Mateusz Zbigniew Durbacz

mateusz zbigniew durbacz
Graduate student Department of Molecular Biology, UT Southwestern Medical Center Dallas

Mateusz is a graduate student in Dr. Eric N. Olson’s lab under the Genetics, Development and Disease graduate program at UT Southwestern Medical Center. His research focuses on developing and testing new AAV mutants with improved safety profiles for Duchenne muscular dystrophy, alongside an alternative delivery approach using lipid nanoparticles (LNPs). He is using CRISPR-based genome-editing strategies to correct DMD mutations in relevant disease models.

Publications:     

1.  Optimized genomic editing of a common Duchenne muscular dystrophy mutation in patient-derived muscle cells and a new humanized mouse model. Durbacz M.Z. et al (2025) Molecular Therapy Nucleic Acids

2. Net39 protects muscle nuclei from mechanical stress during the pathogenesis of Emery-Dreifuss muscular dystrophy. Durbacz M.Z. et al (2023) Journal of Clinical Investigation